Friday, 22 Feb 2019

Scientists are trying to create the brain of the ancient human and install it to the robot


IllustrationIllustration - A group of researchers are trying to create an ancient human brain and will install it into the robot. DNA of ancient creatures, a gene-editing tool called CRISPR, and artificial organs using stem cells. These three things are tried to combine by genetic experts from the University of Carolina, San Diego (UCSD) to 'regenerate' early humans to Earth.

The three aspects mentioned above are utilized to make the brain of Neanderthal, one of the primordial human species. Alysson Muotri, a geneticist from UCSD, says that he and his team have combined the stem cells with Neanderthal DNA to create a collection of tissues that resemble a large cerebral cortex, the outermost layer of the brain.

When compared with an artificial brain created from the outermost layer of human cells, the Neanderthal organoid has a difference in terms of its neuronal form and tissue. The difference is predicted to affect the ability of these species in socializing."We are trying to recreate the minds of the Neanderthals" Muotri said, as quoted by Sciencemag, Monday, July 9th 2018.

In this study, Muotri and his team focused on about 200 genes that distinguish between Neanderthals and modern humans. Known as NOVA1, these aspects played a role in early stage development in the modern human brain, which also has a connection in the occurrence of autism and schizophrenia.

Then, in the early stages of making these early human brains, they begin with epidermal cells belonging to people who have neither genetic abnormalities nor neurological disorders and reset their genomes to turn them into stem cells. Then, with CRISPR, they enter the cell base from Neanderthals into NOVA1 to replace modern humans.


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